
How much does Spravato cost in NYC? Spravato (esketamine) treatment generally costs between $600 and $900 per dose before insurance, with a full treatment course often totaling several thousand dollars over the first few months. The exact amount depends on your dosage, how many sessions you need, and whether insurance helps cover the medication and the in-office monitoring that comes with it.
At Alfredo Nudman Medical PC in Cedarhurst, NY, treatment is led by Alfredo Nudman, a renowned diagnostician and expert psychopharmacologist with over 35 years of experience in psychiatry and academic medicine, including time at Cornell University Medical School. The practice operates on a self-pay basis and does not accept insurance, so patients are responsible for the full cost of treatment.
Spravato is a nasal spray approved by the FDA for adults with treatment-resistant depression and for depressive symptoms in people with major depression who have suicidal thoughts. The total cost is more than just the price of the spray — it’s a comprehensive protocol where each component adds to the final expense:
Initial Evaluation: A 60-minute full diagnostic evaluation with Alfredo Nudman is required to confirm eligibility. At our Cedarhurst practice, this is $1,000.
The Spravato Medication: The cost of the esketamine nasal spray device itself, which can run several hundred dollars per dose.
Clinical Observation: A mandatory two-hour monitoring period in a certified medical office after each dose, covering clinical supervision and facility use during this critical safety window.
In a high-cost area like Cedarhurst, facility and provider fees tend to be higher than in other parts of the country.
No two treatment plans look exactly alike, which is why the total investment depends entirely on your personalized plan. Understanding how much does Spravato cost in NYC involves considering several key factors.
Spravato is prescribed in set doses — typically 56 mg or 84 mg — and a higher dose generally costs more. Alfredo Nudman determines the right dose based on how you respond; some patients start lower and move up, while others stay steady. The initial “induction phase” is the most intensive, then sessions become less frequent as you stabilize, spreading the cost over time.
The total number of sessions varies from person to person, and your response to the medication determines the schedule:
Month 1 (Induction): Twice weekly — about eight sessions.
Month 2: Typically once weekly.
Maintenance: Once every week or every two weeks, depending on your response.
How much does Spravato cost in NYC is directly affected by the number of sessions your individual plan calls for. Alfredo Nudman carefully monitors your progress to ensure you receive neither too few nor too many treatments.
Spravato can only be given at a certified healthcare location meeting FDA safety requirements, since patients need monitoring for side effects like dizziness, drowsiness, or changes in blood pressure. At our practice, this two-hour observation occurs under the direct supervision of Alfredo Nudman, reflecting his pioneering work with ketamine-based therapies. In Cedarhurst, where overhead and real estate costs are higher, these facility and monitoring fees can be more substantial than in lower-cost regions.
While we can only provide an exact quote after your initial evaluation, here are general estimates to help you plan.
The wholesale price of the Spravato device typically falls in the $600 to $900 range, with higher doses landing at the upper end. When you add the two-hour monitoring fee, the all-in cost per single session can range from $800 to over $1,500.
For the initial induction phase of eight treatments, the total investment can range from approximately $6,400 to $12,000 or more, in addition to the initial evaluation fee. Maintenance treatment continues the cost over time, though less frequently. This reflects the comprehensive care and deep expertise you receive.
Cost should never be the only thing standing between you and effective treatment.
Janssen CarePath: The manufacturer of Spravato offers this savings program, which can lower out-of-pocket medication costs for eligible patients with commercial insurance.
Patient Assistance: Additional options may be available based on income and insurance status.
Financing: While our practice does not offer a standing financing program, arrangements can be set up on a case-by-case basis.
It’s also worth exploring whether other treatments fit your situation and budget. The practice offers a range of approaches for depression and anxiety, including Ketamine Infusions and Nitrous Oxide Therapy, which may be discussed alongside Spravato.
Spravato typically costs $600 to $900 per dose before insurance, with a full treatment course reaching several thousand dollars over the first few months. Your final cost depends on dosage, number of sessions, facility fees, and any savings programs. If you’re struggling with treatment-resistant depression and exploring your options, the first step is a comprehensive evaluation with Alfredo Nudman to determine if Spravato is right for you.

About the Author
Alfredo Nudman, MD

June 28, 2026